Chao Chen is a Senior Director of Clinical Pharmacology at GSK. His academic training was in clinical pharmacy and in vivo pharmacology. He started working in drug R&D 30 years ago at Roche, later moved to GSK. While in industry, he has built teams to support drug development from pre-clinical candidate selection to regulatory submission and post-approval activities. He has worked in the areas of translational pharmacology and pharmacometrics on CNS, cardiovascular, autoimmunity, infection, respiratory and rare diseases. The focus of his work is to enhance disease-drug system understanding, translation reliability, development efficiency, registration rigour and decision quality.