Dr. Cornelis “Marcel” Hop is Vice-President at Genentech and manages the Drug Metabolism and Pharmacokinetics department.  He leads a team of about 90 scientists involved in acquisition and interpretation of ADME data in support of drug discovery and development ranging from early stage research to NDA and beyond.  He is also a member of various strategic decision-making bodies at Genentech.  Before that, he was a Senior Director at Pfizer and a Senior Research Fellow at Merck.  He has extensive experience in ADME sciences with a particular focus on PK optimization, human PK and dose prediction, biotransformation, bioanalysis and the use of artificial intelligence and machine learning in drug discovery.  He has authored more than 190 publications and made more than 90 external oral presentations.  In addition, he co-authored two of the best-selling books in the ADME field: Drug Metabolism and Pharmacokinetics Quick Guide and Discovery DMPK Quick Guide.  He has served on various committees for ISSX, the IQ Consortium, academic industrial advisory boards and the Tuberculosis Drug Accelerator.